1/9/2023 0 Comments Winnonlin auc calculationThe concentration-time profiling of ENR within the plasma specimens was determined by considering the non-compartmental analysis (NCA). We analyzed the PK characteristics of ENR and its metabolite ciprofloxacin (CIP) following a single subcutaneous (s.c.) injection of ENR (1.25, 2.5, 5, 10 mg/kg). coli disease model was established via selected E. Of all the tested strains, the PK-PD and E. coli strains were found to be nearest to the MIC 50 i.e. ![]() Whereas, the MIC 50 value calculation was considered as the population PD parameter for ENR against E. coli strains to ENR was calculated using CLSI guidelines. The minimum inhibitory concentration (MIC) distribution of 67 isolated E. ![]() We aim to develop the clinical applications of Enrofloxacin against colibacillosis by using the neutropenic mice thigh infection model. Enrofloxacin is an antibacterial drug with broad-spectrum activity that is widely indicated for veterinary use.
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